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KMID : 0882419960510050693
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Korean Journal of Medicine
1996 Volume.51 No. 5 p.693 ~ p.700
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A Case Report of Mononeuritis Mulitiplex and Vasculitis in Association with Anti-neutrophil Cytoplasmic Autoantibody
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류혜영
손경환/이무열/강흥선/임천규/김권삼/정경천/성동욱/김명식
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Abstract
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Mononeuritis multiplex is known to occur in many illness including certain types of systemic vasculitis, ANCA has been described in association with Wegener's granulomatosis, polyarteritis nodosa, and pauci-immune necrotizing crescentic
glomerulonephritis, since it was first reported in 1982 by Davis et al in patients who had necrotizing glomerulonephritis with no immune deposits. ANCA may well be useful in distinguishing cases mediated by vasculitis from those produced by other
processes, especially early in the course of a disease.
We report a case of mononeuritis multiplex due to ANCA associated vasculitis. We diagnosed vasculitis neuropathy by sural nerve biopsy and angiography. The patient was treated with prednisolone and oral cyclophosphamide Her subjective symptoms
and
objective signs were improved. Subsequent examination of ANCA was negative.
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KEYWORD
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